Does Anyone know how hard or if its possible to put Skyline R33 Front end on Nissan 240sx s13 92 hatchback.

Its possible! There will be some modifications on the 240sx frame but nothing major! Make sure the bolts on the front grill and headlights will fit snug and line up smooth! You will need some brackets for the front lights and grill! I have shops that work on my SILVIA that are good at that type of conversion in LA, CA! It will be a great look... keep it up!